The case of Valeria permits us to state that there are no specific contraindications. If you find yourself in this situation, it is best to consult with your gynecologist in order to get competent, personalized advice on your real needs. According to studies, the use of the estrogen-progestin pill or other combined hormonal contraceptives (CHCs) is associated with increased levels of the thyroid hormones thyroxine (T4), triiodothyronine (T3) and cortisol, which are induced by the increased activity of the globulin protein that binds the hormone thyroxine, (TBG), and the globulin protein that binds the corticosteroid hormones, (CBG). According to various studies, the amount of thyroid hormones T3, T4 and free cortisol in the circulation, as well as the function of the thyroid and adrenal glands, remain unchanged while taking the pill or other combined hormonal contraceptives.
