Some studies have shown that active folic acid and arginine amino acid (L-ARG) act synergistically to facilitate a proper start to pregnancy. Together they favor implantation and vascularization during the periconceptional period, starting from ovulation. Choosing a supplement that contains both is advisable: the coexistence of the two substances enables synergistic action at the molecular level, where the activity of L-ARG is enhanced by the presence of folate in the synthesis of nitric oxide or nitric oxide (NO), a gas mediator that regulates endothelium-dependent vasodilation.
